Review on ecological interactions of the Cochliomyia hominivorax fly and assessment of the possible impacts of its eradication in Uruguay




Cochliomyia hominivorax, eradication, ecological impact, ecological interactions, functional redundancy


Controlling a pest species raises questions about the harmful effects its eradication could cause in ecosystems. Currently, in Uruguay are being analyzed strategies to eradicate the New World Screwworm (NWS), Cochliomyia hominivorax (Diptera: Calliphoridae), an obligatory ectoparasite that causes myiasis in warm-blooded vertebrates, including humans. The loss of a species implies a risk of secondary extinctions and cascading effects that depend on the ecological function of the species and the capacity of the rest of the species with which it interacts to compensate for its loss. To assess the ecological impact of the NWS eradication, we analyzed its ecological redundancy, its effect as an indirect regulatory agent for other species, and its participation in critical ecosystem functions. We conclude that the NWS presents high functional redundancy in most ecological interactions. It does not play an essential role as a regulatory agent of other species and does not play an important role in critical ecosystem functions. Without ignoring the information gaps that certainly exist about the ecological interactions network of the NWS in Uruguay, we estimate that its eradication is unlikely to cause secondary extinctions or cascading effects in the networks it integrates. In order to timely detect possible impacts during the course of the program, it is recommended to monitor the ecosystems using indicators related to direct and indirect partners in the ecological interactions of the NWS.


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Abdallah SI, Rocha UF, Serra OP, Oba MS, Serra RG. Miíase primária em búfalos--Bubalos bubalis L., 1758--do Estado de São Paulo, Brasil, por Cochliomyia hominivorax (Coquerel, 1858), Diptera Calliphoridae [Prymary myiasis in buffaloes--Bufalos bubais L., 1758--of the state of São Paulo, Brazil, by Cochliomyia hominivorax (Coquerel, 1858), Diptera Calliphoridae]. Rev Farm Bioquim Univ Sao Paulo. 1970;8(1):135-8.

Altuna M, Hickner PV, Castro G, Mirazo S, Pérez de León AA, Arp AP. New World screwworm (Cochliomyia hominivorax) myiasis in feral swine of Uruguay: One Health and transboundary disease implications. Parasit Vectors. 2021;14(1):26. doi:10.1186/s13071-020-04499-z. DOI:

Azeredo-Espin AM, Madeira NG. Primary myiasis in dog caused by Phaenicia eximia (Diptera:Calliphoridae) and preliminary mitochondrial DNA analysis of the species in Brazil. J Med Entomol. 1996;33(5):839-43. doi:10.1093/jmedent/33.5.839. DOI:

Basmadjián Y, González Arias M, Galiana A, Palma L, González Curbelo M, Acosta G, Rosa R, Gezuele E. Primera notificación de miasis amigdalina humana por Cochliomyia hominivorax (Coquerel, 1858) en Uruguay. In: VIII Jornadas de Zoología del Uruguay [Internet]. Montevideo: Sociedad Zoologica del Uruguay; 2005 [cited 2022 Aug 19]. p. 37. Available from:

Baumgartner DL, Greenberg B. The Genus Chrysomya (Diptera: Calliphoridae) in the New World. J Med Entomol. 1984;21(1):105-13. doi:10.1093/jmedent/21.1.105. DOI:

Bermúdez SE, Espinosa JD, Cielo AB, Clavel F, Subía J, Barrios S, Medianero E. Incidence of myiasis in Panama during the eradication of Cochliomyia hominivorax (Coquerel 1858, Diptera: Calliphoridae) (2002-2005). Mem Inst Oswaldo Cruz. 2007;102(6):675-9. doi:10.1590/s0074-02762007005000074. DOI:

Bonino Morlan J, Casaretto A. Principales patologías en los actuales sistemas de producción ovina del Uruguay: una puesta al día. In: XL Jornadas Uruguayas de Buiatría. Paysandú: CMVP; 2012. p.19-29.

Brodie JF, Redford KH, Doak DF. Ecological function analysis: incorporating species roles into conservation. Trends Ecol Evol. 2018;33(11):840-50. doi:10.1016/j.tree.2018.08.013. DOI:

Brown VR, Bowen RA, Bosco-Lauth AM. Zoonotic pathogens from feral swine that pose a significant threat to public health. Transbound Emerg Dis. 2018;65(3):649-59. doi:10.1111/tbed.12820. DOI:

Cansi ER, Bonorino R, Mustafa VS, Guedes KMR. Multiple parasitism in wild maned wolf (Chrysocyon brachyurus, Mammalia: Canidae) in Central Brazil. Comp Clin Path. 2012;21(4):489-93. doi:10.1007/s00580-012-1513-7. DOI:

Cansi ER. Caracterização das miíases em animais nas cidades de Brasília (Distrito Federal) e Formosa (Goiás) [doctoral’s thesis]. Brasília (BR): Universidade de Brasília; 2011. 120p.

Carrão DL, Hernandez JMF, Cardoso JD, Correia TR, Araújo JL, Ubiali DG. Dacryoadenitis caused by Cochliomyia macellaria (Diptera: Calliphoridae) in a sambar deer (Rusa unicolor) in Rio de Janeiro, Brazil. Vet Parasitol Reg Stud Reports. 2021;23:100504. doi:10.1016/j.vprsr.2020.100504. DOI:

Christen JA. Molecular-Based Identification of the New World Screwworm, Cochliomyia hominivorax (Coquerel) (Diptera: Calliphoridae) [doctoral’s thesis]. Lincoln (US): University of Nebraska; 2008. 215p.

Clement SL, Hellier BC, Elberson LR, Staska RT, Evans MA. Flies (Diptera: Muscidae: Calliphoridae) are efficient pollinators of Allium ampeloprasum L. (Alliaceae) in field cages. J Econ Entomol. 2007;100(1):131-5. doi:10.1603/0022-0493(2007)100[131:fdmcae];2. DOI:

Coronado A, Kowalski A. Current status of the New World screwworm Cochliomyia hominivorax in Venezuela. Med Vet Entomol. 2009;23(Suppl 1):106-10. doi:10.1111/j.1365-2915.2008.00794.x. DOI:

Costamagna SR, Visciarelli EC, Lucchi LD, Basabe NE, Esteban MP, Oliva A. Aportes al conocimiento de los dípteros ciclorrafos en el área urbana de Bahía Blanca (provincia de Buenos Aires), Argentina. Rev Mus Argent Cienc Nat. 2007;9(1):1-4. DOI:

De Souza JR, Pires MS, Sanavria A. Influência d o clima e da cobertura de solo na mortalidade de Cochliomyia hominivorax (coquerel, 1958) (Diptera: Calliphoridae) e na atuação de seus inimigos naturais. Biosci J. 2010;26(1):136-46.

Dufek MI, Oscherov EB, Damborsky MP, Mulieri PR. Assessment of the Abundance and Diversity of Calliphoridae and Sarcophagidae (Diptera) in Sites With Different Degrees of Human Impact in the Iberá Wetlands (Argentina). J Med Entomol. 2016;53(4):827-35. doi:10.1093/jme/tjw045. DOI:

Estrada-Peña A, Venzal JM, Mangold AJ, Cafrune MM, Guglielmone AA. The Amblyomma maculatum Koch, 1844 (Acari: Ixodidae: Amblyomminae) tick group: diagnostic characters, description of the larva of A. parvitarsum Neumann, 1901, 16S rDNA sequences, distribution and hosts. Syst Parasitol. 2005;60(2):99-112. doi:10.1007/s11230-004-1382-9. DOI:

Farkas R, Hall MJ, Bouzagou AK, Lhor Y, Khallaayoune K. Traumatic myiasis in dogs caused by Wohlfahrtia magnifica and its importance in the epidemiology of wohlfahrtiosis of livestock. Med Vet Entomol. 2009;23(Suppl 1):80-5. doi:10.1111/j.1365-2915.2008.00772.x. DOI:

Felska M, Wohltmann A, Makol J. A synopsis of host-parasite associations between Trombidioidea (Trombidiformes: Prostigmata, Parasitengona) and arthropod hosts. Syst Appl Acarol. 2018;23(7):1375-479. doi:10.11158/saa.23.7.14. DOI:

Figueiredo MAP, Santos ACG, Guerra R de MSNC. Ectoparasitos de animais silvestres no Maranhão. Pesqui Vet Bras. 2010;30(11):988-90. doi:10.1590/s0100-736x2010001100013. DOI:

Fresia P, Pimentel S, Iriarte V, Marques L, Durán V, Saravia A, Novas R, Basika T, Ferenczi A, Castells D, Saporiti T, Cuore U, Losiewicz S, Fernández F, Ciappesoni G, Dalla-Rizza M, Menchaca A. Historical perspective and new avenues to control the myiasis-causing fly Cochliomyia hominivorax in Uruguay. Agrocienc Urug. 2021;25(2):e974. doi:10.31285/AGRO.25.974 DOI:

González Arias M, Romero S, González M, Galiana A, Basmadjián Y. Miasis en niños hospitalizados en el Centro Hospitalario Pereira Rossell, Uruguay, 2001-2004. In: XIX Congreso Latinoamericano de Parasitología: libro de resúmenes [Internet]. [place unknown]: Sociedad Científica del Paraguay; 2009 [cited 2022 Aug 19]. p. 257.

Gracia MJ, Ruíz de Arcaute M, Ferrer LM, Ramo M, Jiménez C, Figueras L. Oestrosis: parasitism by Oestrus ovis. Small Rumin Res. 2019;181(January):91-8. doi:10.1016/j.smallrumres.2019.04.017. DOI:

Grisi L, Leite RC, Martins JR, Barros AT, Andreotti R, Cançado PH, León AA, Pereira JB, Villela HS. Reassessment of the potential economic impact of cattle parasites in Brazil. Rev Bras Parasitol Vet. 2014;23(2):150-6. doi:10.1590/s1984-29612014042. DOI:

Guimarães J, Papavero N, do Prado A. As miíases na região neotropical (identificação, biologia, bibliografia). Rev bras zool. 1983;1:239­416. DOI:

Hall M, Wall R. Myiasis of human and domestic animals. Adv Parasitol. 1995;35:256-333. DOI:

Heath AC. Beneficial aspects of blowflies (Diptera: Calliphoridae). N Z Entomol. 1982;7(3):343-8. doi:10.1080/00779962.1982.9722422. DOI:

Kehoe R, Frago E, Sanders D. Cascading extinctions as a hidden driver of insect decline. Ecol Entomol. 2021;46(4):743-56. doi:10.1111/EEN.12985. DOI:

Klassen W, Curtis C. History of the Sterile Insect Technique. In: Dyck V, Hendrichs J, Robinson A, eds. Sterile insect technique: principles and practice in area-wide integrated pest management. Boca Raton: CRC Press; 2005. p. 3-36.

Little VA. General and Applied Entomology. 3rd ed. New York: Harper & Row; 1972. 527p.

López VG, Romero MI, Parra-Henao G. Gastric and intestinal myiasis due to Ornidia obesa (Diptera: Syrphidae) in humans: first report in colombia. Revista MVZ Córdoba. 2017;22(1):5755-60. doi:10.21897/rmvz.935. DOI:

Luz RT, Azevedo WTA, Silva AS, Lessa CSS, Maia VC, Aguiar VM. Population fluctuation, influence of abiotic factors and the height of traps on the abundance and richness of Calliphoridae and Mesembrinellidae. J Med Entomol. 2020;57(6):1748-57. doi:10.1093/jme/tjaa092. DOI:

Lyra ML, Hatadani LM, de Azeredo-Espin AM, Klaczko LB. Wing morphometry as a tool for correct identification of primary and secondary New World screwworm fly. Bull Entomol Res. 2010;100(1):19-26. doi:10.1017/S0007485309006762. DOI:

Madeira NG. Would Chrysomya albiceps (Diptera: Calliphoridae) be a beneficial species? Arq Bras Med Vet Zootec. 2001;53(2):1-5. doi:10.1590/S0102-09352001000200004. DOI:

Manchini T, Fulgueiras P, Fente A. Miasis oral: a propósito de un caso. Odontoestomatologia. 2009;11(12):38-43.

Martínez M, Remedios M, Goñi B. Lista de los Calliphoridae (Diptera: Muscoporpha) del Uruguay. Bol Soc zoológica Urug. 2016;25(1):35-51.

Martins TF, Lado P, Labruna MB, Venzal JM. El género Amblyomma (Acari: Ixodidae) en Uruguay: especies, distribución, hospedadores, importancia sanitaria y claves para la determinación de adultos y ninfas. Veterinaria (Montevideo). 2014;50(193):26-41.

May-Junior JA, Fagundes-Moreira R, Souza VB, Almeida BA, Haberfeld MB, Sartorelo LR, Ranpim LE, Fragoso CE, Soares JF. Dermatobiosis in Panthera onca: first description and multinomial logistic regression to estimate and predict parasitism in captured wild animals. Rev Bras Parasitol Vet. 2021;30(1):e023820. doi:10.1590/S1984-29612021003. DOI:

McGarry JW, Gusbi AM, Baker A, Hall MJ, El Megademi K. Phoretic and parasitic mites infesting the New World screwworm fly, Cochliomyia hominivorax, following sterile insect releases in Libya. Med Vet Entomol. 1992;6(3):255-60. doi:10.1111/j.1365-2915.1992.tb00615.x. DOI:

Moretti TC, Thyssen PJ. Miíase primária em coelho doméstico causada por Lucilia eximia (Diptera: Calliphoridae) no Brasil: relato de caso. Arq Bras Med Vet Zootec. 2006;58(1):28-30. doi:10.1590/s0102-09352006000100005. DOI:

Nava S, Venzal JM, Labruna MB, Mastropaolo M, González EM, Mangold AJ, Guglielmone AA. Hosts, distribution and genetic divergence (16S rDNA) of Amblyomma dubitatum (Acari: Ixodidae). Exp Appl Acarol. 2010;51(4):335-51. doi:10.1007/s10493-009-9331-6. DOI:

Norris KR. The bionomics of blow flies. Annu Rev Entomol. 1965;10:47-68. DOI:

Oliveira PE, Rech AR. Floral biology and pollination in Brazil: history and possibilities. Acta Bot Bras. 2018;32(3):321-8. DOI:

Paulo DF, Junqueira ACM, Arp AP, Vieira AS, Ceballos J, Skoda SR, Pérez-de-León AA, Sagel A, McMillan WO, Scott MJ, Concha C, Azeredo-Espin AML. Disruption of the odorant coreceptor Orco impairs foraging and host finding behaviors in the New World screwworm fly. Sci Rep. 2021;11(1):11379. doi:10.1038/s41598-021-90649-x. DOI:

Petchey OL, Eklöf A, Borrvall C, Ebenman B. Trophically unique species are vulnerable to cascading extinction. Am Nat. 2008;171(5):568-79. doi:10.1086/587068. DOI:

Pulgar E, Quijada J, Bethencourt A, de Román EM. Reporte de un caso de miasis por Cochliomyia hominivorax (Coquerel, 1858) (Diptera: Calliphoridae) en un cunaguaro (Leopardus pardalis, Linnaeus, 1758) en cautiverio tratado con Doramectina. Entomotropica. 2009;24(3):129-33.

Reck J, Marks FS, Rodrigues RO, Souza UA, Webster A, Leite RC, Gonzales JC, Klafke GM, Martins JR. Does Rhipicephalus microplus tick infestation increase the risk for myiasis caused by Cochliomyia hominivorax in cattle? Prev Vet Med. 2014;113(1):59-62. doi:10.1016/j.prevetmed.2013.10.006. DOI:

Reichard RE. Area-wide biological control of disease vectors and agents affecting wildlife. Rev Sci Tech. 2002;21(1):179-85. doi:10.20506/rst.21.1.1325. DOI:

Remedios M. Ficha zoológica: Dermatobia hominis Linnaeus, 1781 (Diptera: Oestridae). Noticias de la SZU. 2016;9(34):38-9.

Risch DR, Ringma J, Price MR. The global impact of wild pigs (Sus scrofa) on terrestrial biodiversity. Sci Rep. 2021;11(1):13256. doi:10.1038/s41598-021-92691-1. DOI:

Rodrigues-García C. Radiomarcacao de Chrysomya megacephala (Fabricius, 1794) (Diptera, Calliphoridae) e criacao de Belonuchus rufipennis (Fabricius, 1801) (Coleoptera, Staphulinidae) em ovos desta mosca [doctoral’s thesis]. São Paulo (BR): Universidad Estadual de São Paulo; 1993. 88p.

Rodrigues-Guimarães R, Guimarães RR, De Carvalho RW, Mayhé-Nunes AJ, Moya-Borja GE. Registro de Aphaereta laeviuscula (Spinola) (Hymenoptera: Braconidae) e Nasonia vitripennis (Walker) (Hymenoptera: Pteromalidae) como parasitóide de Cochliomyia hominivorax (Coquerel) (Diptera: Calliphoridae), no estado do Rio de Jane. Neotrop Entomol. 2006;35(3):402-7. doi:10.1590/s1519-566x2006000300017. DOI:

Rodríguez Diego J, Olivares Orozco J, Sánchez Castilleja Y, Arece García J. El Gusano Barrenador del Ganado, Cochliomyia hominivorax (Diptera: Calliphoridae): un problema en la salud animal y humana. Rev Salud Anim. 2016;38(2):120-30.

Rusch TW, Adutwumwaah A, Beebe LEJ, Tomberlin JK, Tarone AM. The upper thermal tolerance of the secondary screwworm, Cochliomyia macellaria Fabricius (Diptera: Calliphoridae). J Therm Biol. 2019;85:102405. doi:10.1016/j.jtherbio.2019.102405. DOI:

Saeed S, Naqqash MN, Jaleel W, Saeed Q, Ghouri F. The effect of blow flies (Diptera: Calliphoridae) on the size and weight of mangos (Mangifera indica L.). PeerJ. 2016;4:e2076. doi:10.7717/peerj.2076. DOI:

Sanders D, Sutter L, van Veen FJ. The loss of indirect interactions leads to cascading extinctions of carnivores. Ecol Lett. 2013;16(5):664-9. doi:10.1111/ele.12096. DOI:

Sanders D, Thébault E, Kehoe R, van Veen FJ. Trophic redundancy reduces vulnerability to extinction cascades. Proc Natl Acad Sci U S A. 2018;115(10):2419-24. doi:10.1073/pnas.1716825115. DOI:

Saracho-Bottero MN, Venzal JM, Tarragona EL, Thompson CS, Mangold AJ, Beati L, Guglielmone AA, Nava S. The Ixodes ricinus complex (Acari: Ixodidae) in the Southern Cone of America: Ixodes pararicinus, Ixodes aragaoi, and Ixodes sp. cf. I. affinis. Parasitol Res. 2020;119(1):43-54. doi:10.1007/s00436-019-06470-z. DOI:

Schnack JA, Mariluis JC, Centeno N, Muzon J. Composición específica, ecología y sinantropía de Calllphoridae (Insecta: Diptera) en el Gran Buenos Aires. Rev Soc Entomol Arg. 1995;54(1-4):161-71.

Spradbery P. Screwworm fly: a tale of two species. Agricultural Zoology Reviews. 1994;6:1-42.

USDA. Biological Assessment for a New World Screwworm Eradication Program in South Florida. Washington: USDA; 2017. 26p.

Valledor MS, Petraccia L, Cabral P, Castro O, Décia L, Xavier V, Altuna M, Marques L, Casás G, Dominguez D, Lado P. Resultados del Diagnostico de Bicheras Obtenidas en el Departamento de Artigas Durante 13 Semanas (Enero – Abril 09). In: 6tas Jornadas Técnicas de Facultad de Veterinaria. Montevideo: Facultad de Veterinaria; 2009. p. 130­1.

Vargas-Terán M, Spradbery JP, Hofmann HC, Tweddle NE. Impact of screwworm eradication programmes using the sterile insect technique. In: Dyck VA, Hendrichs J, Robinson AS, editors. Sterile insect technique: principles and practice in area-wide integrated pest management. 2nd ed. Boca Raton: CRC Press; 2021. p. 949-78. DOI:

Venzal JM, Castro O, Cabrera PA, de Souza CG, Guglielmone AA. Las garrapatas de Uruguay: especies, hospedadores, distribución e importancia sanitaria. Veterinaria (Montevideo). 2003;30(150-151):17-28.

Viera C, editor. Arácnidos de Uruguay: diversidad, comportamiento y ecología. Montevideo: Ediciones de la Banda Oriental; 2011. 237p.

Welch JB. Predation by Spiders on Ground-Released Screwworm Flies, Cochliomyia hominivorax (Diptera: Calliphoridae) in a Mountainous Area of Southern Mexico. J Arachnol. 1993;21(1):23-8.

Wendt LW. Fauna parasitária de capivaras (Hydrochoerus hydrochaeris Linnaeus, 1766) em sistema de criação semi-intensivo, na região sul do Rio Grande do Sul [master’s thesis]. Pelotas (BR): Universidade Federal de Pelotas; 2009. 54p.



How to Cite

Etchevers I, Iriarte MV, Marques L, Ferenczi A, Dalla Rizza M, Marzaroli J, et al. Review on ecological interactions of the Cochliomyia hominivorax fly and assessment of the possible impacts of its eradication in Uruguay. Agrocienc Urug [Internet]. 2022 Sep. 16 [cited 2024 Jun. 15];26(2):e1056. Available from:



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